Scientist

Job Description

Position Summary

The Scientist will be responsible for the design, synthesis, purification, characterization, and analytical evaluation of peptides and peptide-related biomolecules and/or polyssacharides. The role requires hands-on expertise in Solid Phase Peptide Synthesis (SPPS), bioanalytical techniques, HPLC/UPLC method development, and characterization using modern analytical tools such as LC-MS. The candidate will contribute to new product development, process optimization, technical troubleshooting, and cross-functional collaborations with Quality, Product Management.

Key Responsibilities

• Design and execute peptide synthesis using Fmoc-based Solid Phase Peptide Synthesis (SPPS).

• Perform peptide cleavage, purification, and isolation using preparative and analytical HPLC.

• Develop and optimize HPLC/UPLC methods for peptide and biomolecule analysis.

• Conduct bioanalytical studies including purity assessment, impurity profiling, and stability evaluation.

• Characterize synthesized products using LC-MS, UPLC, UV-Vis spectroscopy, and related analytical techniques.

• Troubleshoot synthetic and analytical challenges and recommend process improvements.

• Maintain detailed documentation in ELN and prepare technical reports.

• Support new product development and technology transfer activities.

• Collaborate with QC, QA, Manufacturing, Product Management, and external research partners.

• Ensure compliance with laboratory safety, quality, and regulatory requirements.

Technical Skills

• Strong knowledge of Biochemistry and Molecular Biology.

• Hands-on experience in Solid Phase Peptide Synthesis (SPPS).

• Experience with peptide purification and characterization.

• Expertise in HPLC/UPLC method development and troubleshooting.

• Knowledge of bioanalytical techniques and biomolecule characterization.

• Familiarity with LC-MS/MS and mass spectrometric analysis.

• Understanding of peptide impurities, metabolites, and degradation pathways.

• Experience in data analysis and technical report writing.

• M.Sc/M.Tech 2-3 Years

  M.Sc/M.Tech (Bio

  
  

  chemistry/Biotechnology/Analytical Chemistry)

Contract Duration One Year

Contract is extendable